Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Phenylbutyrate Na

N° du produit ABIN1027851

Aperçu rapide pour Phenylbutyrate Na (ABIN1027851)

  • Fonction

    HDAC inhibitor

    Attributs du produit

    Histone deacetylase inhibitor.

    Pureté

    >98 %

    Chemical Name

    Sodium 4-phenylbutanoate, 4-PB

    Formula

    C10H11NaO2

    Solubility

    Soluble to 1100 mM in water and 100 mM in DMSO
  • Commentaires

    Source: Synthetic.
    Appearance: White solid

    Restrictions

    For Research Use only
  • Format

    Solid

    Précaution d'utilisation

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

    Conseil sur la manipulation

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

    Stock

    -20 °C
  • Sujet

    Sodium phenylbutyrate is metabolized in the human body by beta-oxidation to phenylacetate, which is then conjugated with glutamine to phenylacetylglutamine, which is eliminated with urine. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of gamma-globin gene.

    Poids moléculaire

    186.18

    Numéro CAS

    1716-12-7
Vous êtes ici:
Chat with us!